All it takes: grain, water and yeast!
Quantities
    Approximately 100 kg (222 lbs) grain will make 600 liter mash. The expected 
    end result is 32-35 liter pure (theoretically 100%) alcohol, from which we 
    can make about 80-87 liter (21-23 gallon) whiskey that has the strength of 
    80 proof.
Grinding
    This stage is simple: grind the grain into a course meal (you want a consistency 
    similar to what is required for beer).
Mashing
    Next, you will mash in your ground malt barley, mixed with water, in the mash 
    tun that can be identical to a brewer's mash tun.. This process also known 
    as "sugaring" or "conversion", when we convert the starch 
    into sugar resulting in a liquid "wort". How much time this process 
    takes is well known for brewers: depends on the size of the tank and amount 
    of mash. 
Separating 
    the Wort
    To separate the wort, the mash is sieved through a false bottom screen plate 
    at the bottom of the tank. The liquid is then drained to a fermentation tank 
    and the remaining wet grains can be disposed of or used as animal feed.
Fermenting
    Unless you cultivate your own yeast, you should use new yeast for every new 
    batch of liquid wort you ferment. Fermentation, usually taking 2 to 3 days, 
    begins once the yeast is added and should take place at about 95 degrees Fahrenheit. 
    
Distilling
    The number of rounds to distill, once again, depends on the taste the distiller 
    desires. Keep in mind that every run through the still increases the purity 
    of the whiskey. If using a regular pot still, or alembic, note that only a 
    little more than half of the water content is actually removed, an inefficient 
    process but still allowing for some variation. Traditionally, the Scotch whisky 
    is distilled twice and the Irish whiskey three times. For this reason, the 
    Irish claim their whiskey is a smoother and purer whiskey.
Don't forget about the unwanted runoffs while distilling: the "heads", an undesirable and poisonous liquid, boils off first before the ethanol begins to burn; discard of the "tails", as well, as they fall below 80 proof and do not add to the quality of the whiskey. The ideal distillate sought for in whiskey falls around 80 proof.
Maturation
    Finally, the whiskey matures in oak casks. The legal minimum when aging whiskey 
    is 3 years. During this maturation process the whiskey "breathes" 
    in the barrel, gaining aroma, flavor and color. Aging, sometimes referred 
    to as mellowing, takes the edge off the raw whiskey and creates what we know 
    as the smooth whiskey. Also, during the aging process, a percentage of the 
    alcohol evaporates. This evaporated alcohol is called the "angels' share".